SELZENTRY was specially designed to target R5 HIV, a common type of HIV. To find out if you have R5 HIV, you can be prescreened with an HIV tropism test (sometimes called a tropism assay). This can let you see right away if SELZENTRY could be part of your personalized HIV therapy program.
A tropism test is a blood test that reveals how your HIV enters T-cells. HIV can enter T-cells via an R5 or X4 co-receptor. A tropism test reveals which of these receptors your HIV uses.
You have R5-tropic HIV if HIV uses the R5 co-receptors to enter your T-cells. You have X4-tropic HIV if HIV uses the X4 co-receptors to enter your T-cells. You have dual or mixed tropic HIV if HIV uses both the R5 and the X4 co-receptors to enter your T-cells.
SELZENTRY® (maraviroc) is a CCR5 inhibitor that is used with other HIV medicines to treat CCR5-tropic HIV. SELZENTRY is not recommended in patients with dual/mixed or CXCR4-tropic HIV. It is for adult patients with CCR5-tropic HIV only. A tropism test is needed before starting SELZENTRY. SELZENTRY does not cure HIV infection or AIDS and does not lower the risk of passing HIV to other people.
People taking SELZENTRY may still develop infections, including opportunistic infections or other conditions that happen with HIV infection. The long-term effects of SELZENTRY are not known at this time. It is very important that you stay under the care of your healthcare provider during treatment with SELZENTRY.
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